Genomic erosion and extensive horizontal gene transfer in gut-associated Acetobacteraceae.
Bryan P BrownJennifer J WernegreenPublished in: BMC genomics (2019)
Using comparative genomics, our study reveals substantial changes in genomic content in persistent associates of the insect gastrointestinal tract and provides evidence for the evolutionary pressures inherent to this environment. We describe patterns of genomic erosion and horizontal acquisition that result in mosaic metabolic pathways. Accordingly, the phylogenetic position of both strains of these associates form a divergent, monophyletic clade sister to gut associates of honey bees and more distantly to Gluconobacter.