The effect of previous treatment with bisphosphonate and renal impairment on the response to denosumab in osteoporosis: a 'real-life' study.
T R FraserI FlogaitisA E MooreGeeta HampsonPublished in: Journal of endocrinological investigation (2019)
Denosumab increases BMD following previous bisphosphonate treatment and is comparable to zoledronate. Lower response seen at the hip in CKD is related to PTH concentrations.