Interstitial lung abnormalities and interstitial lung diseases associated with cigarette smoking in a rural cohort undergoing surgical resection.
Rahul G SanganiVishal DeepakAndrew J GhioMichael J ForteRafia ZulfikarZalak PatelAustin KingEsra AlshaikhnassirGhulam AbbasJeffrey VosPublished in: BMC pulmonary medicine (2022)
In a rural cohort undergoing surgical resection, radiographic subclinical ILAs/ILDs patterns were highly prevalent and associated with ever smoking and intensity of smoking. The presence of radiographic ILA/ILD patterns and isolated honeycomb changes were associated with increased mortality. Subclinical ILAs/ILDs and histologic fibrosis correlated with clinical COPD as well as radiographic and pathologic emphysema emphasizing the co-existence of these pulmonary injuries in a heavily smoking population.
Keyphrases
- smoking cessation
- chronic obstructive pulmonary disease
- south africa
- lung function
- pulmonary hypertension
- neoadjuvant chemotherapy
- cardiovascular events
- interstitial lung disease
- idiopathic pulmonary fibrosis
- high intensity
- cardiovascular disease
- cystic fibrosis
- type diabetes
- lymph node
- air pollution
- systemic sclerosis
- radiation therapy
- coronary artery disease
- rectal cancer