Endocannabinoid receptor CB2R is significantly expressed in aspirin-exacerbated respiratory disease: a pilot study.
Alessia CorradoMonica BattleSarah K WiseF Eun-Hyung LeeDavid M GuidotJohn M DelGaudioSamuel A MolinaJoshua M LevyPublished in: International forum of allergy & rhinology (2018)
The endocannabinoid system is an emerging immunomodulatory network that may be involved in AERD. This is the first study of CB2R in sinonasal disease, showing significantly increased transcription in nasal polyps from subjects with AERD. Additional study is warranted to further evaluate the contribution and therapeutic potential of this novel finding in chronic rhinosinusitis.