Maternal rheumatoid arthritis and risk of autism in the offspring.
Weiyao YinMattias NorrbäckStephen Z LevineNatalia RiveraJoseph D BuxbaumHailin ZhuBenjamin YipAbraham ReichenbergJohan AsklingSven SandinPublished in: Psychological medicine (2023)
In Sweden, maternal RA before delivery was associated with an increased risk of offspring ASD. The comparable association between maternal arthralgia and ASD risk suggests other pathways of risk than autoimmunity/inflammation, acting jointly or independently of RA.
Keyphrases
- rheumatoid arthritis
- autism spectrum disorder
- birth weight
- disease activity
- pregnancy outcomes
- intellectual disability
- high fat diet
- attention deficit hyperactivity disorder
- ankylosing spondylitis
- oxidative stress
- systemic lupus erythematosus
- adipose tissue
- weight gain
- gestational age
- type diabetes
- idiopathic pulmonary fibrosis
- body mass index