Perilaldehyde activates AMP-activated protein kinase to suppress the growth of gastric cancer via induction of autophagy.

Yu ZhangSuosi LiuQin FengXiuyun HuangXiangyang WangYa PengZhihong ZhaoZhan Liu

Published in: Journal of cellular biochemistry (2018)

PAH increases AMPK phosphorylation and activity to induce gastric cancer cell autophagy to inhibit the growth of gastric cancer. In perspective, therapy of PAH should be applied to treat patients with gastric cancer.

Keyphrases

protein kinase
cell death
endoplasmic reticulum stress
signaling pathway
oxidative stress
skeletal muscle
stem cells
bone marrow