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Do genetic risk scores for childhood adiposity operate independent of BMI of their mothers?

Lam O HuangCamilla S MorgenLars H ÄngquistEllen A NohrTuomas O KilpeläinenTorben HansenThorkild I A SørensenTheresia M Schnurr
Published in: International journal of obesity (2005) (2021)
GRSs for childhood adiposity are strongly associated with childhood adiposity even when adjusted for maternal BMI, suggesting that the child-specific GRSs and maternal BMI contribute to childhood overweight independent of each other. However, high maternal BMI may attenuate the effects of child GRSs in children.
Keyphrases
  • weight gain
  • birth weight
  • body mass index
  • early life
  • insulin resistance
  • childhood cancer
  • mental health
  • pregnancy outcomes
  • young adults
  • physical activity
  • skeletal muscle
  • gene expression