Methylglyoxal: a novel upstream regulator of DNA methylation.

Gaurav DubeAssia TiamiouMartin BizetYasmine BoumahdImène GasmiRebekah CrakeJustine BellierMarie-Julie NokinEmilie CalonneRachel DeplusTom WissocqOlivier PeulenVincent CastronovoFrançois FuksAkeila Bellahcène

Published in: Journal of experimental & clinical cancer research : CR (2023)

This study emphasizes the importance of MG oncometabolite, occurring downstream of the Warburg effect, as a novel epigenetic regulator and proposes MG scavengers to reverse altered patterns of gene expression in TNBC.

Keyphrases

dna methylation
gene expression
genome wide
transcription factor