Further evidence for the role of WNT10A, WNT10B and GREM2 as candidate genes for isolated tooth agenesis.

Sonia MagruderEmily CarterMeredith A WilliamsJeryl EnglishSercan AkyalcinAriadne Letra

Published in: Orthodontics & craniofacial research (2018)

Our findings further support a role for variants in WNT10A, WNT10B and GREM2 genes in the aetiology of isolated tooth agenesis. Functional studies are necessary to investigate the biological effects of these gene variants in tooth agenesis phenotypes.

Keyphrases

cell proliferation
stem cells
copy number
genome wide
genome wide analysis