Low plasma protein Z levels are associated with an increased risk for perioperative bleedings.

Clemens HinterleitnerKlaus-Peter KreisselmeierAnn-Christin PecherPaul-Stefan MauzLothar KanzHans-Georg KoppKarl G Jaschonek

Published in: European journal of haematology (2018)

Low PZ appears to be an underestimated risk factor for perioperative bleeding. Determination of PZ plasma concentrations might be useful in the preoperative workup in patients with a bleeding history, when detailed clotting analyses remain inconclusive.

Keyphrases

patients undergoing
cardiac surgery
atrial fibrillation
protein protein
solid phase extraction
small molecule
high resolution
simultaneous determination