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Angiopoietin-1 deficiency increases tumor metastasis in mice.

Iacovos P MichaelMartina OrebrandMarta LimaBeatriz PereiraOlga VolpertSusan E QuagginMarie Jeansson
Published in: BMC cancer (2017)
This study show that loss of the Angiopoietin-1/Tek vascular growth factor system leads to increased metastasis without affecting primary tumor growth.
Keyphrases
  • growth factor
  • skeletal muscle
  • metabolic syndrome