Cells from subcutaneous tissues contribute to scarless skin regeneration in Xenopus laevis froglets.

Rina Otsuka-YamaguchiAiko Kawasumi-KitaNanako KudoYumi IzutsuKoji Tamura Hitoshi Yokoyama

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2017)

Cells derived from subcutaneous tissues, at least in the trunk region, contribute to and may be essential for skin regeneration. Characterizing the subcutaneous tissue-derived cells that contribute to skin regeneration in amphibians may lead to the induction of cells that can regenerate complete skin structures without scarring in mammals. Developmental Dynamics 246:585-597, 2017. © 2017 Wiley Periodicals, Inc.

Keyphrases

induced apoptosis
wound healing
stem cells
cell cycle arrest
soft tissue
gene expression
endoplasmic reticulum stress
signaling pathway
high resolution
cell proliferation
cell free