Effect of galectin-1 on prognosis and responsiveness of immune checkpoint plus tyrosine kinase inhibition in renal cell carcinoma.

Jiajun WangSihong ZhangYing WangYanjun ZhuXianglai Xu Jianming Guo

Published in: Cancer medicine (2024)

High galectin-1 indicated therapeutic resistance and shorter PFS of IO/TKI therapy. High galectin-1 also indicated CD8+ T cell dysfunction. High galectin-1 could be applied for patient selection of IO/TKI therapy in RCC.

Keyphrases

tyrosine kinase
renal cell carcinoma
epidermal growth factor receptor
advanced non small cell lung cancer
mesenchymal stem cells
cell therapy