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Prevalence and impact of multidrug-resistant bacteria in solid cancer patients with bloodstream infection: a 25-year trend analysis.

Carlos LoperaPatricia MonzóTommaso Francesco AielloMariana ChumbitaOlivier PeyronyAntonio Gallardo-PizarroCristina PitartGuillermo CuervoLaura MorataMarta BodroSabina HerreraAna Del RíoJosé Antonio MartínezAlex SorianoPedro Puerta-AlcaldeCarolina García-Vidal
Published in: Microbiology spectrum (2024)
Multidrug-resistant (MDR) bacteria pose a global public health threat as they are more challenging to treat, and they are on the rise. Solid cancer patients are often immunocompromised due to their disease and cancer treatments, making them more susceptible to infections. Understanding the changes and trends in bloodstream infections in solid cancer patients is crucial, to help physicians make informed decisions about appropriate antibiotic therapies, manage infections in this vulnerable population, and prevent infection. Solid cancer patients often require intensive and prolonged treatments, including surgery, chemotherapy, and radiation therapy. Infections can complicate these treatments, leading to treatment delays, increased healthcare costs, and poorer patient outcomes. Investigating new strategies to combat MDR infections and researching novel antibiotics in these patients is of paramount importance to avoid these negative impacts.
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