Causality between heart failure and epigenetic age: a bidirectional Mendelian randomization study.
Fengjun ZhangShanshan DengJing ZhangWenchang XuDexian XianYuxuan WangQiong ZhaoYuan LiuXiuli ZhuMin PengLin ZhangPublished in: ESC heart failure (2023)
The bidirectional MR analysis demonstrated a causal link between genetically predicted epigenetic age and HF in individuals of European descent. Further research into epigenetic age in other populations and additional genetic information related to HF is warranted.