MEM: An Algorithm for the Reliable Detection of Microsatellite Instability (MSI) on a Small NGS Panel in Colorectal Cancer.

Guillaume HerbreteauFabrice AiraudElise Pierre-NoëlAudrey ValléeStéphane BézieauSandrine ThéoleyreHélène BlonsSimon GarinetMarc Guillaume Denis

Published in: Cancers (2021)

the MEM algorithm can determine the MSI status of colorectal cancer samples on a small NGS panel, using only five microsatellites approved by international guidelines, and can be combined with screening for targetable mutations.

Keyphrases

machine learning
deep learning
clinical practice
loop mediated isothermal amplification
real time pcr
genetic diversity
quantum dots