The effect of sphingosine-1-phosphate on the endothelial glycocalyx during ischemia-reperfusion injury in the isolated rat heart.

Hala AraibiElizabeth van der MerweAsfree GwanyanyaRoisin Kelly-Laubscher

Published in: Microcirculation (New York, N.Y. : 1994) (2020)

These results suggest that sphingosine-1-phosphate-induced cardioprotection against ischemia-reperfusion injury is not mediated by the maintenance of syndecan-1 in the endothelial glycocalyx.

Keyphrases

ischemia reperfusion injury
endothelial cells
high glucose
oxidative stress
diabetic rats
heart failure
drug induced