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The wild bootstrap for multivariate Nelson-Aalen estimators.

Tobias BluhmkiDennis DoblerJan BeyersmannMarkus Pauly
Published in: Lifetime data analysis (2018)
We rigorously extend the widely used wild bootstrap resampling technique to the multivariate Nelson-Aalen estimator under Aalen's multiplicative intensity model. Aalen's model covers general Markovian multistate models including competing risks subject to independent left-truncation and right-censoring. This leads to various statistical applications such as asymptotically valid confidence bands or tests for equivalence and proportional hazards. This is exemplified in a data analysis examining the impact of ventilation on the duration of intensive care unit stay. The finite sample properties of the new procedures are investigated in a simulation study.
Keyphrases
  • data analysis
  • intensive care unit
  • mechanical ventilation
  • high intensity
  • genetic diversity
  • high resolution
  • respiratory failure
  • risk assessment
  • single molecule