Survival of BRCA1/BRCA2-associated pT1 breast cancer patients, a cohort study.
Mark van BareleAmy RiebornBernadette A M Heemskerk-GerritsenInge-Marie ObdeijnLinetta B KoppertClaudette E LooRob A E M TollenaarMargreet G E M AusemsIrma van de BeekLieke P V BergerMaaike de BoerLiselot P van HestC Marleen KetsMatti Rookusnull nullMarjanka K SchmidtAgnes JagerMaartje J HooningPublished in: Breast cancer research and treatment (2022)
Smaller tumor size is associated with better OS and less lymph node involvement in pT1 BRCA1/2-associated BC patients. The results suggest that early detection in BRCA1/2 mutation carriers of pT1a/b BC may reduce mortality and the need for systemic therapy.