Detection of prostate cancer-specific transcripts in extracellular vesicles isolated from post-DRE urine.
Kathryn L PellegriniDattatraya PatilKristen J S DouglasGrace LeeKathryn WehrmeyerMersiha TorlakJeremy ClarkColin S CooperCarlos S MorenoMartin G SandaPublished in: The Prostate (2017)
Post-DRE urine EVs are a viable source of prostate-derived RNAs for biomarker discovery and prostate cancer status can be distinguished from analysis of these specimens. Continued analysis of urine EVs offers the potential discovery of novel biomarkers for pre-biopsy prostate cancer detection.