Evaluation of possible pharmacokinetic interaction between methotrexate and proton pump inhibitors in rats.
Hinata UedaKatsuya NarumiYu SatoAyako FurugenMasaki KobayashiKen IsekiPublished in: Pharmacological reports : PR (2020)
Esomeprazole increases the t1/2 of MTX in rats, which may be partially attributed to the inhibition of rOAT3.