Plasma VP8∗-Binding Antibodies in Rotavirus Infection and Oral Vaccination in Young Bangladeshi Children.
Benjamin LeeE Ross ColgateMarya CarmolliDorothy M DicksonSoyeon GullicksonSean A DiehlRifat AraMasud AlamGolam KibriaMd Abdul KaderSajia AfreenTahsin FerdousRashidul HaqueBeth D KirkpatrickPublished in: Journal of the Pediatric Infectious Diseases Society (2022)
This work suggests that VP8∗-binding antibodies may not be sufficient or necessary for protection from RV gastroenteritis following prior RV infection or oral vaccination; the role of VP8∗ antibodies induced by parenteral vaccination with non-replicating vaccines remains to be determined.