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Identification of two autoantigens recognised by circulating autoantibodies as potential biomarkers for diagnosing giant cell arteritis.

Elisa PesceMauro BombaciStefania CrociMartina BonaciniChiara MarvisiCaterina RicordiSara MontiFrancesco MuratoreSergio AbrignaniRoberto CaporaliMaria Orietta BorghiCarlo SalvaraniPeter M VilligerRenata GrifantiniPier Luigi Meroni
Published in: Clinical and experimental rheumatology (2024)
Detecting GCA-specific autoantibodies may offer a new, non-invasive tool for improving our diagnostic power in GCA. Even though cell-mediated immune responses are crucial for GCA pathogenesis, this finding opens the way for investigating the additional role of humoral immune responses in the disease.
Keyphrases
  • immune response
  • giant cell
  • systemic lupus erythematosus
  • dendritic cells
  • toll like receptor
  • single cell
  • cell therapy
  • stem cells
  • inflammatory response
  • bone marrow