Impact of neurofibromatosis type 1 with plexiform neurofibromas on the health-related quality of life and work productivity of adult patients and caregivers in the UK: a cross-sectional survey.

Hyun Kyoo YooAlex PorteousAlvin NgKeval HariaAnnabel GriffithsAndrew LloydXiaoqin YangGbenga KazeemVolkan Barut

Published in: BMC neurology (2023)

NF1 PN worsens adult patient and caregiver HRQoL compared to the general population, notably affecting pain and discomfort, anxiety and depression and caregiver productivity.

Keyphrases

climate change
chronic pain
signaling pathway
case report
palliative care
pain management
lps induced
neuropathic pain
oxidative stress
pi k akt
nuclear factor
immune response
spinal cord injury
inflammatory response
cell proliferation