Evaluation of DEFB1 polymorphisms in individuals with chronic periodontitis and diabetes mellitus type 2 in a population of northeastern Brazil.

Rayanne Soraia Aguiar de Melo Dias Roberto Carlos Mourão Pinho Felipe Rodrigues de Almeida Francisco Alfredo Farias Bandeira Ronaldo Celerino da SilvaSergio CrovellaBruna de Carvalho Farias Vajgel Renata Cimões

Published in: Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry (2018)

The results indicate that genetic variations of DEFB1 gene (SNP-20: G allele and GA and GG genotypes) and the DEFB1 5'UTR haplotypes (GCG and ACG) may be associated with a susceptibility to CP in DM2 individuals as well as CP individuals without DM2.

Keyphrases

genome wide
copy number
pet ct
glycemic control
type diabetes
dna methylation
gene expression
metabolic syndrome
transcription factor
high density