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Immunotherapy with single agent nivolumab for advanced leiomyosarcoma of the uterus: Results of a phase 2 study.

Eytan Ben-AmiConstance M BarysauskasSarah SolomonKadija TahlilRita MalleyMelissa HohosKathleen PolsonMargaret LoucksMariano SevergniniTara PatelAmy CunninghamScott J RodigF Stephen HodiJeffrey A MorganPriscilla MerriamAndrew J WagnerGeoffrey I ShapiroSuzanne George
Published in: Cancer (2017)
Single-agent nivolumab did not demonstrate a benefit in this cohort of previously treated advanced ULMS patients. Further biomarker-driven approaches and studies evaluating combined immune checkpoint-modulators should be considered. Cancer 2017;123:3285-90. © 2017 American Cancer Society.
Keyphrases
  • papillary thyroid
  • end stage renal disease
  • newly diagnosed
  • squamous cell
  • ejection fraction
  • chronic kidney disease
  • small molecule
  • prognostic factors
  • peritoneal dialysis
  • squamous cell carcinoma
  • clinical trial