Oral contraceptives do not modify the risk of a second attack and disability accrual in a prospective cohort of women with a clinically isolated syndrome and early multiple sclerosis.
Susana Otero-RomeroPere Carbonell-MirabentLuciana MidagliaMaría ZuluagaIngrid GalánÁlvaro Cobo-CalvoJordi RíoGeorgina ArrambideÁngela Vidal-JordanaJoaquín CastilloBreogan Rodriguez AcevedoManuel ComabellaMarta RodríguezCarmen TurCristina AugerÀlex RoviraJaume Sastre-GarrigaXavier MontalbanMar TintorePublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2021)
OC use does not modify the risk of second attack or disability accrual in patients with CIS and early MS, once considered as a time-dependent exposure and adjusted by other potential confounders.