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MicroRNA-138 promotes the progression of multiple myeloma through targeting paired PAX5.
Xiao Yan
Keting Wang
Cong Shi
Kaihong Xu
Binbin Lai
Shujun Yang
Lixia Sheng
Ping Zhang
Ying Chen
Qitian Mu
Guifang Ouyang
Published in:
Mutation research (2024)
Taken together, miR-138 plays a carcinogenic role in MM, and miR-138 adjusted the proliferation and apoptosis of MMSC by targeting PAX5. miR-138 has the probability of becoming a new medicinal target for the treatment of MM.
Keyphrases
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cell proliferation
long non coding rna
long noncoding rna
multiple myeloma
signaling pathway
endoplasmic reticulum stress
cell death
drug delivery
cancer therapy
combination therapy
polycyclic aromatic hydrocarbons
smoking cessation