Automated immunohistochemical quantification of hypoxia biomarkers shows correlation with dysplastic epithelial changes.
Omar KujanIsmail SiddiquiChristopher LeeMajdy IdreesKate ShearstonCamile S FarahPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2023)
Hypoxia-associated events are observed during early epithelial dysplastic changes and have a potential role in oral carcinogenesis. The level of hypoxia may assist in stratifying the severity of epithelial changes among patients with oral leukoplakia.