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The common variant of rs6214 in insulin like growth factor 1 (IGF1) gene: a potential protective factor for non-alcoholic fatty liver disease.

Mohammad SabzikarianTouraj MahmoudiSeidamir Pasha TabaeianGholamreza RezamandAsadollah AsadiHamid FarahaniHossein NobakhtReza DabiriFariborz Mansour-GhanaeiFaramarz DerakhshanMohammad Reza Zali
Published in: Archives of physiology and biochemistry (2020)
To our knowledge, these findings suggest, for the first time, that the IGF1 rs6214 "A" allele and "AA + AG" genotype have protective effects for NAFLD susceptibility. Nonetheless, further studies are needed to validate our findings.
Keyphrases
  • growth hormone
  • binding protein
  • healthcare
  • pi k akt
  • copy number
  • genome wide
  • quantum dots
  • liver fibrosis
  • risk assessment
  • dna methylation
  • cell proliferation
  • genome wide identification
  • genome wide analysis