Glomerular and tubular effects of dapagliflozin, eplerenone and their combination in patients with chronic kidney disease: A post-hoc analysis of the ROTATE-3 study.
Tom T G F LieverseMaria J PuchadesUdo D J MulderMichele ProvenzanoGuido KrenningNiels JongsSimon E WinkRiemer H J A SlartMichele AndreucciLuis D' MarcoLuca De NicolaJose L GorrizHiddo J Lambers HeerspinkPublished in: Diabetes, obesity & metabolism (2023)
Dapagliflozin and eplerenone exert different effects on markers of glomerular and tubular function supporting the hypothesis that different mechanistic pathways may account for their kidney protective effects.