Impact of mutations in homologous recombination repair genes on treatment outcomes for metastatic castration resistant prostate cancer.
Alexander S CarlsonRigo I AcevedoDaniel M LimRoman GulatiAgnes GawneAlexandra O SokolovaHeather H ChengPeter S NelsonR Bruce MontgomeryEvan Y YuMichael T SchweizerPublished in: PloS one (2020)
HR gene mutational status was associated with comparable clinical outcomes following treatment with ARSIs or taxane-based chemotherapy. Additional prospective studies are needed to confirm these findings.