Assessment of Allergen-Responsive Regulatory T Cells in Experimental Asthma Induced in Different Mouse Strains.

Carolina Trindade de Azevedo A C Cotias Ana Carolina de Arantes T P T Ferreira Marco Aurélio Martins Priscilla C Olsen

Published in: Mediators of inflammation (2021)

Treg cells may play different roles in asthma control. Similar to asthmatic individuals, the lack of an efficient regulatory response and susceptibility to the development of experimental asthma in A/J mice further suggests that this strain could be preferably chosen in experimental models of allergic asthma.

Keyphrases

allergic rhinitis
lung function
chronic obstructive pulmonary disease
regulatory t cells
cystic fibrosis
induced apoptosis
dendritic cells
air pollution
escherichia coli
type diabetes
transcription factor
metabolic syndrome
immune response
signaling pathway
drug induced
endoplasmic reticulum stress
pi k akt