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Propagation of a rapid cell-to-cell H 2 O 2 signal over long distances in a monolayer of cardiomyocyte cells.

Yosef FichmanLinda RowlandThi Thao NguyenShi-Jie ChenRon Mittler
Published in: bioRxiv : the preprint server for biology (2023)
accumulation along its path. The signal propagates over several centimeters changing the redox state of cells.Changes in the abundance of hundreds of proteins accompanies the signal.The cell-to-cell signal requires paracrine and juxtacrine signaling.
Keyphrases
  • single cell
  • cell therapy
  • induced apoptosis
  • stem cells
  • cell cycle arrest
  • signaling pathway
  • bone marrow
  • angiotensin ii
  • endoplasmic reticulum stress
  • sensitive detection