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Promotion of Differentiating Bone Marrow Mesenchymal Stromal Cells (BMSCs) into Cardiomyocytes via HCN2 and HCN4 Cotransfection.

Xue LuoHongxiao LiXiaolin SunQisheng ZuoBichun LiYe ZhuWei WeiXiang Gu
Published in: BioMed research international (2021)
HCN2 and HCN4 overexpression can considerably enhance the MSC ability to differentiate into cardiomyocytes in vitro and restore the ionic current.
Keyphrases
  • bone marrow
  • mesenchymal stem cells
  • cell proliferation
  • transcription factor
  • high glucose
  • contrast enhanced