Age at diagnosis, glycemic trajectories, and responses to oral glucose-lowering drugs in type 2 diabetes in Hong Kong: A population-based observational study.
Calvin KeTherese A StukelBaiju R ShahEric LauRonald Ching-Wan MaWing-Yee SoAlice P KongElaine Y K ChowJuliana Chung Ngor ChanAndrea On Yan LukPublished in: PLoS medicine (2020)
In this study, we observed excess glycemic exposure and rapid glycemic deterioration in young-onset T2D, indicating that improved treatment strategies are needed in this setting. The differential responses to OGLDs between young- and usual-onset T2D suggest that better disease classification could guide personalized therapy.