High levels of circulating TNFR1 increase the risk of all-cause mortality and progression of renal disease in type 2 diabetic nephropathy.
Gema Maria Fernandez JuarezJavier Villacorta PerezJosé Luis Luño FernándezErnesto Martinez-MartinezVictoria CachofeiroVicente Barrio LuciaAna M Tato RiberaAngel Mendez AbreuAlfredo CordonJesus Angel Oliva DominguezManuel Praga TerentePublished in: Nephrology (Carlton, Vic.) (2017)
Our results show that the highest levels of TNFR1 are independently associated with progression of renal disease and death in type 2 DN. The renin angiotensin blockers have no effect on these inflammatory markers.