Predictors for the Development of Neurological Immune-related Adverse Events of Immune Checkpoint Inhibitors and Impact on Mortality.

Chen YanMerry HuangCarol SwetlikKarlo ToljanAhmad Z MahadeenJames BenaAmy KunchokPauline FunchainMarisa McGinley

Published in: European journal of neurology (2023)

Neuro-irAEs are not associated with increase in overall mortality. Potential predictors for the development of neuro irAEs are younger age, melanoma, prior chemotherapy and resection, CTLA-4, or combination ICI exposure.

Keyphrases

cardiovascular events
risk factors
locally advanced
squamous cell carcinoma
cardiovascular disease
brain injury
human health
climate change