Changes in Peripheral Blood Eosinophil Counts and Risk of Eosinophilic Granulomatosis with Polyangiitis Onset after Initiation of Dupilumab Administration in Adult Patients with Asthma.
Yoshitomo KushimaYasuo ShimizuHiromi HoshiRyo AraiNaoya IkedaYusuke NakamuraMeitetsu MasawaHiroaki OkutomiNana YazawaKazuyuki ChibanaAkihiro TakemasaSeiji NihoPublished in: Journal of clinical medicine (2023)
Physicians should check for the onset of EGPA by monitoring the elevation of eosinophils within 6 months after dupilumab administration, especially in patients with PBE counts greater than 1500 cells/μL at 3 months.