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Kappa Free Light Chains in Cerebrospinal Fluid in Inflammatory and Non-Inflammatory Neurological Diseases.

Franz Felix KonenPhilipp SchwenkenbecherKonstantin Fritz JendretzkyStefan GingeleTorsten WitteKurt-Wolfram SühsMatthias GrotheMalte Johannes HannichMarie SüßeThomas Skripuletz
Published in: Brain sciences (2022)
The determination of both biomarkers (KFLC and oligoclonal bands) is recommended for routine diagnosis and differentiation of non-inflammatory and inflammatory neurological diseases. Due to the high sensitivity and physiological considerations, the assessment of KFLC in the Reiber's diagram should be preferred to other evaluation methods.
Keyphrases
  • oxidative stress
  • cerebrospinal fluid
  • nuclear factor
  • toll like receptor
  • high resolution
  • brain injury
  • blood brain barrier
  • solid phase extraction
  • cerebral ischemia
  • liquid chromatography