Flightless-I governs cell fate by recruiting the SUMO isopeptidase SENP3 to distinct HOX genes.

Arnab NayakAnja ReckChristian MorsczeckStefan Müller

Published in: Epigenetics & chromatin (2017)

Altogether, these data reveal a crucial functional interconnection of FLII with the sumoylation machinery that converges on epigenetic regulation and cell fate determination.

Keyphrases

cell fate
genome wide
electronic health record
solid phase extraction
big data
dna methylation
single cell
molecularly imprinted
gene expression
machine learning
deep learning