Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders.
Muhammad ImranFereshteh GhoratIahtisham Ul-HaqHabib Ur-RehmanFarhan AslamMojtaba HeydariMohammad Ali ShariatiEleonora OkuskhanovaZhanibek YessimbekovThiruvengadam MuthuMohammad Hashem HashempurMaksim RebezovPublished in: Antioxidants (Basel, Switzerland) (2020)
Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant and a non-pro-vitamin A carotenoid. Lycopene has been found to be efficient in ameliorating cancer insurgences, diabetes mellitus, cardiac complications, oxidative stress-mediated malfunctions, inflammatory events, skin and bone diseases, hepatic, neural and reproductive disorders. This review summarizes information regarding its sources and uses amongst different societies, its biochemistry aspects, and the potential utilization of lycopene and possible mechanisms involved in alleviating the abovementioned disorders. Furthermore, future directions with the possible use of this nutraceutical against lifestyle-related disorders are emphasized. Its protective effects against recommended doses of toxic agents and toxicity and safety are also discussed.
Keyphrases
- oxidative stress
- human health
- anti inflammatory
- risk assessment
- dna damage
- diabetic rats
- climate change
- ischemia reperfusion injury
- soft tissue
- induced apoptosis
- metabolic syndrome
- cardiovascular disease
- risk factors
- papillary thyroid
- left ventricular
- physical activity
- heart failure
- health information
- bone mineral density
- healthcare
- weight loss
- squamous cell carcinoma
- insulin resistance
- heat shock protein
- body composition
- skeletal muscle
- bone regeneration
- endoplasmic reticulum stress
- childhood cancer
- lymph node metastasis