Inoperable CASTLE of the thyroid gland treated with radical radiotherapy with complete remission.
Petra KovářováRadovan VojtíšekMichal KrčmaOndřej DaumJan BaxaEmília SukovskáJindřich FínekPublished in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2021)
Carcinoma showing thymus-like elements (CASTLE) is an extremely rare malignant tumor of the thyroid gland and soft tissues of the neck with favorable prognosis. Histological features of the CASTLE are similar to thymic carcinoma, and it is assumed that it arises from the ectopic thymic tissue or the remnants of branchial pouches. The optimal treatment strategy is still uncertain because of the rarity of the tumor. The mainstay of treatment is surgery. The role of other modalities is unclear. We present a case report of a patient with locally advanced CASTLE of the thyroid gland who was not suitable for surgery and underwent radical radiotherapy with subsequent achievement of complete remission. We also present a literature review.
Keyphrases
- locally advanced
- minimally invasive
- rectal cancer
- early stage
- squamous cell carcinoma
- coronary artery bypass
- neoadjuvant chemotherapy
- case report
- gene expression
- phase ii study
- coronary artery disease
- rheumatoid arthritis
- combination therapy
- ulcerative colitis
- surgical site infection
- acute coronary syndrome
- systemic lupus erythematosus
- lymph node
- open label