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Transcriptomic responses to diet quality and viral infection in Apis mellifera.

Lindsay RutterJimena Carrillo-TrippBryony C BonningDianne CookAmy L TothAdam G Dolezal
Published in: BMC genomics (2019)
Through transcriptional contrasts and functional enrichment analysis, we contribute to our understanding of the mechanisms underlying feedbacks between nutrition and disease in bees. We also show that comparing results derived from combined analyses across multiple RNA-seq studies may allow researchers to identify transcriptomic patterns in bees that are concurrently less artificial and less noisy. This work underlines the merits of using data visualization techniques and multiple datasets to interpret RNA-sequencing studies.
Keyphrases
  • rna seq
  • single cell
  • physical activity
  • case control
  • gene expression
  • electronic health record
  • weight loss
  • big data
  • heat shock
  • deep learning
  • heat shock protein