Mucosal penetration and clearance of gluten and milk antigens in eosinophilic oesophagitis.
Anupama RaviEric V MariettaJeffrey A AlexanderKathryn A PetersonCrystal LaveyDebra M GenoJoseph A MurrayDavid A KatzkaPublished in: Alimentary pharmacology & therapeutics (2020)
The oesophageal epithelium is selectively permeable and has relatively long dwell times for food antigens known to trigger EoE. The precise mechanism of antigen-specific mucosal entry and the factors that determine the induction or effector trigger of the Th2 pathway activation merit further study.