The Clinical Application of Urine Soluble CD163 in ANCA-Associated Vasculitis.
Sarah M MoranJennifer ScottMichael R ClarksonNiall ConlonJean DunneMatthew D GriffinTomas P GriffinElizabeth GroarkeJohn HolianConor JudgeJason WyseKirsty McLoughlinPaul V O'HaraMark A LittleMatthias Kretzlernull nullPublished in: Journal of the American Society of Nephrology : JASN (2021)
usCD163 is elevated in renal vasculitis flare and remains low in flare mimics. Nonspecific protein leakage in nephrotic syndrome elevates usCD163 in the absence of glomerular macrophage infiltration, resulting in false-positive results; this can be corrected with urine protein normalization.