Login / Signup

Efficacy of biological therapies and small molecules in moderate to severe ulcerative colitis: systematic review and network meta-analysis.

Nicholas E BurrDavid J GracieChristopher J BlackAlexander Charles Ford
Published in: Gut (2021)
In a network meta-analysis, upadacitinib 45 mg once daily ranked first for clinical remission in all patients, patients naïve to anti-TNF-α drugs and patients previously exposed. Infliximab 10 mg/kg ranked first for endoscopic improvement. Most drugs were safe and well tolerated.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • ulcerative colitis
  • prognostic factors
  • peritoneal dialysis
  • ultrasound guided
  • patient reported