Adjuvant Therapy with Oncolytic Adenovirus Delta-24-RGDOX After Intratumoral Adoptive T-cell Therapy Promotes Antigen Spread to Sustain Systemic Antitumor Immunity.
Hong JiangDong Ho ShinYanhua YiXuejun FanJoy GuminJiasen HeAndrew G GillardFrederick F LangCandelaria Gomez-ManzanoJuan FueyoPublished in: Cancer research communications (2023)
Adjuvant therapy with oncolytic viruses promotes antigen spread to potentiate localized intratumoral adoptive T-cell therapy with limited TAA targets, leading to sustainable systemic antitumor immunity to overcome tumor relapse.