Perillaldehyde Mitigates Ionizing Radiation-Induced Intestinal Injury by Inhibiting Ferroptosis via the Nrf2 Signaling Pathway.

Lin-Feng TangXiaoming MaLi-Wei XieHao ZhouJiahua YuZhen-Xin WangMing Li

Published in: Molecular nutrition & food research (2023)

PAH inhibits ionizing radiation (IR)-induced ferroptosis and attenuates intestinal injury after irradiation by activating Nrf2 signaling. Therefore, PAH is a promising therapeutic strategy for IR-induced intestinal injury.

Keyphrases

signaling pathway
high glucose
diabetic rats
oxidative stress
cell death
drug induced
radiation therapy
cell proliferation
radiation induced
stress induced