WISH-R- a fast and efficient tool for construction of epistatic networks for complex traits and diseases.

Victor A O CarmeloLisette J A KogelmanMajbritt Busk MadsenHaja N Kadarmideen

Published in: BMC bioinformatics (2018)

The WISH-R package is an efficient implementation for analyzing genome-wide epistasis for complex diseases and traits. It includes methods and strategies for analyzing epistasis from initial data filtering until final data interpretation. WISH offers a new way to analyze genomic data by combining epistasis and network based analysis in one method and provides options for visualizations. This alleviates many of the existing hurdles in the analysis of genomic interactions.

Keyphrases

genome wide
electronic health record
big data
copy number
dna methylation
healthcare
primary care
data analysis
mouse model
artificial intelligence